RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ

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United States of America Patent

SERIAL NO

12863772

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Abstract

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A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.

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Patent Owner(s)

Patent OwnerAddress
MEDICAGO INCQUÉBEC QUÉBEC G1V 3V9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Couture, Manon St-Augustin-de-Desmaures, CA 28 143
D'Aoust, Marc-André Quebec, CA 7 34
Dargis, Michéle Quebec, CA 4 55
Landry, Nathalie ST-Romuald, CA 15 108
Lavoie, Pierre-Olivier Quebec, CA 37 105
Ors, Frédéric Quebec, CA 4 49
Trépanier, Sonia Saint-Nicolas, CA 3 37
Vézina, Louis-Philippe Neuville, CA 7 39

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