ORAL DELIVERY OF PROTEINS AND PEPTIDES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20100303901A1
SERIAL NO

12597105

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Enteric coated capsules or tablets for oral delivery of a protein, polypeptide or peptide drug, in particular for oral delivery of insulin, are provided, comprising microparticles of the protein, polypeptide or peptide drug, microparticles of a protease inhibitor and, optionally, microparticles of an absorption enhancer. The protease inhibitor and the absorption enhancer may be together in the same microparticles. The microparticles of each component are embedded in an enteric polymer matrix. The enteric coated tablet or capsule of the invention enables fast release of the protein, polypeptide or peptide drug at different times at desired loci in the gastrointestinal tract

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Patent Owner(s)

Patent OwnerAddress
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD32000 HAIFA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kopelman, Isaiah J Haifa, IL 2 6
Mizrahi, Shimon Haifa, IL 33 357
Nahmias, Yaakov Mevaseret Zion, IL 37 59
Oren, Aharon Kfar Yonah, IL 3 12
Ramon, Ory Sarid, IL 4 37
Salzmann, Nir Hadera, IL 1 6
Shimoni, Eyal Haifa, IL 4 35

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  • 6 Citation Count
  • A61K Class
  • 11.97 % this patent is cited more than
  • 15 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7303334104243222310478582826113401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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