MOUSE MODELS CARRYING A KNOCK-OUT MUTATION OF THE QPCTL-GENE

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United States of America Patent

APP PUB NO 20100299766A1
SERIAL NO

12782953

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Abstract

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A knock-out non-human animal, in particular a mouse, carrying a QPCTL knock-out mutation. Additionally, respective cells and cell lines and methods and compositions for evaluating agents that affect QPCTL, for use in compositions for the treatment of QPCTL-related diseases are disclosed.

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Patent Owner(s)

Patent OwnerAddress
PROBIODRUG AG06120 HALLE/SAALE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cynis, Holger Halle/Saale, DE 20 89
Demuth, Hans-Ulrich Halle/Saale, DE 116 1907
Graubner, Sigrid Muenchen, DE 10 16
Koch, Birgit Amsdorf, DE 4 11
Schilling, Stephan Halle/Saale, DE 51 597
Sedlmeier, Reinhard Muenchen, DE 10 43
Stephan, Anett Halle/Saale, DE 10 11

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