Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease
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United States of America Patent
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Issued Date -
Nov 25, 2010
app pub date -
Sep 4, 2007
filing date -
Sep 7, 2006
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Abstract
The present invention is directed to spiropiperidine compounds of formula (I) and tautomers thereof, which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
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