MUTANT DNA POLYMERASES AND THEIR GENES FROM THERMOCOCCUS
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United States of America Patent
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Issued Date -
Nov 25, 2010
app pub date -
Oct 2, 2007
filing date -
Nov 30, 2006
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Abandoned
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Abstract
sp NA1. strain and produced by site-specific mutagenesis, their amino acid sequences, genes encoding said mutant DNA polymerases, their nucleic acids sequences, recombinant vectors containing said nucleic acids sequences, host cells transformed with thereof and methods for producing mutant DNA polymerase protein by using thereof. As mutant DNA polymerases according to the present invention have increased processivity by site-specific mutagenesis on exonuclease active site compared to wild type DNA polymerase, the present invention is broadly applicable for PCR in various molecular genetic technologies.
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