Purification method of high-molecular-weight polyethylene glycol compound
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United States of America Patent
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Issued Date -
Nov 18, 2010
app pub date -
Mar 31, 2010
filing date -
Mar 31, 2009
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Abstract
An impurity derived from a high-molecular-weight polyethylene glycol compound is removed from a high-molecular-weight polyethylene glycol compound whose total average number of moles of ethylene oxide units added in the molecule is 220 to 4500. In a state where the high-molecular-weight polyethylene glycol compound is dissolved in at least one of water and an organic solvent selected from aromatic hydrocarbon solvents having 8 or less carbon atoms in total and ester compound solvents having 5 or less carbon atoms in total, the water and the organic solvent are mixed. The resulting mixture was separated into an organic layer and an aqueous layer, and the organic layer is separated from the aqueous layer.
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