PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME
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United States of America Patent
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Issued Date -
Nov 18, 2010
app pub date -
Dec 17, 2007
filing date -
Dec 18, 2006
priority date (Note) -
Abandoned
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Abstract
Disclosed is a PNA oligomer with increased solubility in water and specificity upon hybridization with nucleic acid, which comprises at least one universal base, capable of forming a base pair with natural DNA or RNA bases, incorporated in its base sequence, the base sequence having at least 60% purine bases or at least four contiguous purine bases.
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