Antibody Specific Binding to A-Beta Oligomer and the Use
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United States of America Patent
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Issued Date -
Nov 18, 2010
app pub date -
Jul 31, 2009
filing date -
Aug 1, 2008
priority date (Note) -
Abandoned
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Abstract
The present inventors successfully produced monoclonal antibodies that are specific to only soluble Aβ oligomers, but do not recognize soluble Aβ monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.
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