ANTI-INFLAMMATORY COMPOSITION CONTAINING DOCOSAHEXAENOYL LYSOPHOSPHATIDYLAMINE AS AN ACTIVE INGREDIENT
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United States of America Patent
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Issued Date -
Nov 11, 2010
app pub date -
Oct 16, 2009
filing date -
May 6, 2009
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Abandoned
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Abstract
The present invention relates to an anti-inflammatory composition containing docosahexaenoyl lysophosphatidylamine as an active ingredient. Particularly, one of polyunsaturated lysophosphatidylcholines, docosahexaenoyl lysophosphatidylcholine inhibits intracellular NO generation mediated by lipopolysaccharide and suppresses zymosan A induced peritonitis in vivo, suggesting that it has excellent anti-inflammatory effect but has no cytotoxicity, so that it can be effectively used for prevention and treatment of inflammatory disease.
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