HOMOGENIZATION OF A RADIOPHARMACEUTICAL USING SONIFICATION AND/OR ROTOR-STATOR TECHNOLOGY TO PRODUCE A HOMOGENOUS SUSPENSION, EMULSION, MIXTURE OR SOLID SUSPENSION OF IMMISCIBLE INGREDIENTS

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United States of America Patent

APP PUB NO 20100284912A1
SERIAL NO

12745505

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Abstract

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A homogenous dispersion of aqueous droplets of a radiopharmaceutical or radiodiagnostic agent within a non-aqueous medium and method of making the same is provided. The homogenous dispersion is largely free of impurities and constitutes a substantially uniform distribution of sodium thiosulfate and radiopharmaceutical which is stable for a time sufficient to fill and solidify within gel capsules. In making the homogenous dispersion, dry sodium thiosulfate and dry potassium phosphate dibasic anhydrous are uniformly dispersed within non-aqueous, liquid polyethylene glycol.

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Patent Owner(s)

Patent OwnerAddress
BRACCO IMAGING S P A20134 MILANO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Oehlberg, Peter J Plainsboro, US 1 0
Schramm, Ernst Milltown, US 23 433

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