METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF INSULIN
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Jan 8, 2009
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Jan 8, 2008
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Abstract
The present invention provides a pharmaceutical composition formulated for oral delivery of insulin, comprising a particulate non-covalently associated mixture of pharmacologically inert silica nanoparticles having a hydrophobic surface, a polysaccharide, and insulin suspended in an oil. The present invention further provides methods of manufacturing same and therapeutic methods utilizing same for oral delivery of insulin.
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