PRODUCTION AND USE OF EPITOPE-TAGGED HEPATITIS C VIRUS PARTICLE
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United States of America Patent
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Issued Date -
Nov 4, 2010
app pub date -
Jul 11, 2008
filing date -
Jul 13, 2007
priority date (Note) -
Abandoned
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Abstract
This invention relates to a nucleic acid comprising a nucleic acid sequence encoding an epitope tag peptide in the hypervariable region 1 of the E2 protein of naturally occurring or chimeric hepatitis C virus (HCV) genome, an epitope-tagged HCV particle encoded by such nucleic acid, and a method for purifying the HCV particles at a high purity in a simple manner with the use of an anti-epitope tag antibody-immobilized support.
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