DIAGNOSTIC IN VITRO METHOD FOR ASSESSING VON WILLEBRAND DISEASE AND INCREASED BLEEDING RISK ASSOCIATED WITH VON WILLEBRAND DISEASE AND ACQUIRED OR CONGENITAL DISORDERS OF PLATELET FUNCTION

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United States of America Patent

APP PUB NO 20100273206A1
SERIAL NO

12809977

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Abstract

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The invention relates to an in-vitro method for diagnosing Von Willebrand Disease (VWD) and an increased bleeding risk associated with Von Willebrand Disease and/or acquired or congenital platelet function defects that reduce the interactions of Von Willebrand Factor (VWF) with platelets. The in-vitro method of the invention may also be used to diagnose further bleeding risks. The test is suitable for use as a screening test based on whole blood and has the additional benefit of being suitable as a point of care test. The method involves the incubation of a sample containing platelets and hemostasis factors with an activator of platelet aggregation and the measurement of the viscoelastic change after inducing coagulation, e.g., by means of thromboelastography (TEG).

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Patent Owner(s)

Patent OwnerAddress
CSL BEHRING GMBHMARBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rauh, Manfred Frensdorf, DE 1 1
Topf, Hans-Georg Erlangen, DE 1 1

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