DUAL ACTING PHARMACEUTICAL COMPOSITIONS BASED ON SUPERSTRUCTURES OF ANGIOTENSIN RECEPTOR ANTAGONIST/BLOCKER (ARB) AND NE UTRAL ENDOPEPTIDASE (EP) INHIBITOR

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United States of America Patent

APP PUB NO 20100267786A1
SERIAL NO

12741251

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3′-methyl-2′-(pentanoyl{2″-(tetrazol-5-ylate)biphenyl-4′-ylmethyl}amino)butyrate]hemipentahydrate.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS PHARMACEUTICALS CORPORATIONONE HEALTH PLAZA EAST HANOVER NJ 07936

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Al-Fayoumi, Suliman Morristown, US 3 5
Hu, Jiahui Bridgewater, US 9 182
Kumaraperumal, Natrajan Wayne, US 9 43
Royce, Alan E Saylorsburg, US 14 490
Ruegger, Colleen Morris Plains, US 24 64
Zannou, Erika A Edison, US 3 5

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