TREATMENT OF OSTEOARTHRITIS

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United States of America Patent

SERIAL NO

12703178

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to methods of treatment of osteoarthritis, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists of the C5a receptor, and are active against C5a receptors on polymorphonuclear leukocytes and macrophages. Particularly preferred compounds for use in the invention are disclosed.

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Patent Owner(s)

Patent OwnerAddress
PROMICS PTY LIMITEDNEW SOUTH WALES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fairlie, David Springwood, AU 18 69
Shiels, Ian Alexander Muirlea, AU 9 12

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