RECOMBINANT PERFORIN, EXPRESSION AND USES THEREOF
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United States of America Patent
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app pub date -
Feb 12, 2010
filing date -
Mar 1, 2004
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Abandoned
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Abstract
The present invention relates to retroviral vectors capable of driving the expression of perforin in a cell and a method of expressing recombinant perforin in a cell. The present invention also relates to recombinant perforin polypeptides and nucleic acid molecules derived therefrom and uses thereof. Also encompassed are screening assays employing such recombinant perforin molecules, compounds identified by the screening assays and uses thereof.
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