THERAPEUTIC METHOD FOR REDUCING ANGIOGENESIS
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United States of America Patent
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app pub date -
Jun 17, 2010
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Jan 28, 2000
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Abstract
A method of controlling or treating an angiogenic dependent condition in a mammal, preferably in a human by administering an anti angiogenic molecule such as an angiogenesis growth factor antagonist, and a chemotherapeutic agent in amounts and frequencies effective, in combination, to produce a regression or arrest of said condition while minimizing or preventing significant toxicity of the chemotherapeutic agent. Also a kit for controlling or treating an angiogenic dependent condition in a mammal, preferably in a human, comprising an anti-angiogenic molecule, such as an angiogenesis growth factor antagonist, and a chemotherapeutic agent in amounts effective, in combination, to produce a regression or arrest of said condition while minimizing or preventing significant toxicity of the chemotherapeutic agent.
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