Compositions and Methods for Regulating an Immune Response in a Subject

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United States of America Patent

SERIAL NO

12824685

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compositions an methods for regulating an immune response in a subject, particularly to treat a subject with a tumor, notably a solid tumor, or an infectious disease. Disclosed are methods of regulating the innate immunity in a subject, such as by regulating the activity of γδ T cells in a subject. Disclosed are combinations of particular agents, such as a cytokine and a γδ T cell activator, particular administration regimens and dosages can produce a remarkable expansion of γδ T cells in vivo and a remarkable increase in a subject's immune defense. The invention can be used for therapeutic purposes, to produce, regulate or facilitate an immune response in a subject.

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Patent Owner(s)

Patent OwnerAddress
INNATE PHARMA S A13009 MARSEILLE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Belmant, Christian Six-Fours-Les-Plages, FR 22 175
Romagne, Francois La Ciotat, FR 28 380
Sicard, Helene Marseille, FR 8 26
Tiollier, Jerome Marseille, FR 9 169

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