METHOD TO PRODUCE MODIFIED PLANTS WITH ALTERED N-GLYCOSYLATION PATTERN
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United States of America Patent
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Issued Date -
Sep 23, 2010
app pub date -
Oct 31, 2007
filing date -
Oct 31, 2007
priority date (Note) -
Abandoned
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Abstract
Provided is a novel method to produce a plant cell or plant having an altered N-glycosylation pattern resulting, in particular, in a low level of β-1,2-xylose residues and core α-1,3-fucose residues on protein-bound N-glycans. The plant cell or plant is of particular interest for producing therapeutic glycoproteins with a low, or not detectable, level of β-1,2-xylose and α-1,3-fucose residues. Also provided are novel α-1,3-fucosyltransferase nucleotide sequences and uses.
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