DETECTION OF CELL SURFACE BINDING MOLECULES USING A PHAGE DISPLAY BLOCKING ASSAY
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United States of America Patent
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Issued Date -
Sep 23, 2010
app pub date -
Jun 26, 2008
filing date -
Jun 26, 2007
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Abandoned
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Abstract
The present invention relates to the use of a phage blocking assay to determine unknown binding molecule present on or in the surface of a cell, a non-infectious moiety, a bacteria, a virus, or another pathogen. In particular embodiments, the invention relates to the identification of unknown receptors on a cell or virus involved in infection. Further, it relates to the use of said binding molecules, for example virus binding molecules or cellular receptors and binding members with binding specificity to said binding molecules, for example antibodies, in methods of therapy.
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