Liposome for liver-specific delivery and release of therapeutic nucleic acids or drugs
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United States of America Patent
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Nov 27, 2012
Grant Date -
Sep 23, 2010
app pub date -
Jun 1, 2010
filing date -
Nov 9, 2006
priority date (Note) -
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Abstract
Disclosed herein is a composite of a nanoscale particle size. The composite is able to specifically deliver therapeutic agents such as therapeutic nucleic acids or drugs to the liver and selectively release them into hepatic cells to manifest potent therapeutic effects of the therapeutic agents. The composite may be comprised of an apolipoprotein A-1 and a liposome-forming material. A composition containing the composite and a pharmaceutically acceptable carrier is disclosed.
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