Method and Apparatus for Maintenance and Expansion of Hematopoietic Stem Cells From Mononuclear Cells
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Feb 6, 2007
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Feb 6, 2006
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Abstract
A method of expanding/maintaining undifferentiated hematopoietic stem cells by obtaining unselected mononuclear cells; and seeding the mononuclear cells into a stationary phase plug-flow bioreactor in which a three dimensional mesenchymal/stromal cell culture has been pre-established, thereby expanding/maintaining undifferentiated hematopoietic stem cells.
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