SMART CONTRAST AGENT AND METHOD FOR DETECTING TRANSITION METAL IONS AND TREATING RELATED DISORDERS
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Mar 24, 2010
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Nov 26, 2008
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Abstract
The present disclosure provides smart contrast agents for transition metals and a method of using the same. The smart contrast agents include a core peptide and a first labeling group attached to a first end of the core peptide. The smart contrast agents can also include a second labeling group attached to a second end of the core peptide. The core peptide can bind to transition metals, and can be homologous to a fragment selected from the extended octarepeat region of a prion protein.
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