METHODS FOR ASSESSING EFFECTS ON SKELETAL GROWTH
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United States of America Patent
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Issued Date -
Sep 9, 2010
app pub date -
Sep 3, 2009
filing date -
Sep 4, 2008
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Abandoned
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Abstract
A method for assessing effects on growth of skeletal members comprises preparing a culture comprising a skeletal member and a substance whose effect on growth of the skeletal member is to be determined and capturing images of the skeletal member at selected time intervals without terminating growth. The skeletal member may be fully articulated and the substance whose effect on growth is to be determined may be labeled with a marker and tracked over time. The methods of the invention may be used to assess effects on growth through the positioning of the substance in the skeletal member and for drug discovery.
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