Methods and Compositions for Determining Altered Susceptibility of HIV-1 to Protease Inhibitor Treatment
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United States of America Patent
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Issued Date -
Sep 9, 2010
app pub date -
Feb 25, 2008
filing date -
Feb 23, 2007
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Abandoned
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Abstract
This invention relates to methods for determining altered susceptibility of HIV-I viruses to protease inhibitors (PIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding protease and/or gag of the HIV-I, the presence of mutations correlated with altered susceptibility to amprenavir and/or darunavir.
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