PDGFR BETA-SPECIFIC INHIBITORS

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United States of America Patent

SERIAL NO

12764121

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is directed to novel PDGFRβ-specific antagonists. The antagonists include antibodies, which can be bispecific. The antibodies are used to reduce or inhibit tumor growth and or to treat an angiogenic disease. The invention also includes combinations of PDGFRβ-specific antagonists with VEGFR antagonists for such treatments. The antagonists can further be administered in combination with other anti-angiogenic or anti-neoplastic drugs.

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Patent Owner(s)

Patent OwnerAddress
IMCLONE LLCNEW YORK NY 10016

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
SHEN, Juqun Flushing, US 9 68
ZHU, Zhenping Cambridge, US 43 483

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