Human Anti-OPGL Neutralizing Antibodies As Selective OPGL Pathway Inhibitors

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United States of America Patent

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12705962

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Abstract

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Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyle, William J Malibu, US 112 9389
Elliott, Robin L Newbury Park, US 6 71
Huang, Haichun Fremont, US 121 4072
Martin, Frank Newbury Park, US 37 830
Medlock, Eugene Westlake, US 20 257
Sullivan, John K Newbury Park, US 20 417

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