MC-1R, MC-2R, AND/OR MU OPIOID RECEPTORS MODULATION
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United States of America Patent
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Issued Date -
Aug 19, 2010
app pub date -
Jun 6, 2008
filing date -
Jun 6, 2007
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Abandoned
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Abstract
The invention concerns active substances modulating the expression of the receptors of the products of the POMC gene (MC-IR, MC-2R, and the μ opioid receptor), and possibly modulating the expression of POMC in cutaneous cells, notably to modulate the proliferation and differentiation of epidermal cells in order to re-epithelial, maintain innervation, irrigate the skin, or restore normal pigmentation, or to fight against aging, or to modulate pigmentation independently or not of cutaneous aging. The invention also concerns a method of screening such active substances.
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