ANTIBODY CONJUGATES FOR CIRCUMVENTING MULTI-DRUG RESISTANCE

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United States of America Patent

APP PUB NO 20100196403A1
SERIAL NO

12523767

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Abstract

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Conjugates of a cell permeability moiety coupled to an antibody against an intracellular epitope of a multi drug resistance (MDR) protein are provided. Also provided are pharmaceutical compositions that include these conjugates and methods for their use in preventing and inhibiting multi drug resistance to therapeutic agents, particularly to chemotherapeutic agents.

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Patent Owner(s)

Patent OwnerAddress
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD9139002 JERUSALEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hochman, Jacob Jerusalem, IL 7 2
Wellhoener, Hans Hannover, DE 1 1

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