PRODUCTION OF HIGH MANNOSE PROTEINS IN PLANT CULTURE
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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N/A
Issued Date -
N/A
app pub date -
Apr 30, 2008
filing date -
Apr 27, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods for expression and production of enzymatically active high mannose lysosomal enzymes using transgenic plant root, particularly carrot cells. More particularly, the invention relates to host cells, particularly transgenic suspended carrot cells, vectors and methods for high yield expression and production of biologically active high mannose Glucocerebrosidase (GCD). The invention further provides for compositions and methods for the treatment of lysosomal storage diseases.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
PROTALIX LTD | CARMIEL |
International Classification(s)

- 2008 Application Filing Year
- A61K Class
- 9711 Applications Filed
- 5862 Patents Issued To-Date
- 60.37 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Bartfeld, Daniel | Moran- Doar-Na Bikat Beit HaKerem, IL | 19 | 188 |
# of filed Patents : 19 Total Citations : 188 | |||
Baum, Gideon | D.N. Upper Galilee, IL | 16 | 178 |
# of filed Patents : 16 Total Citations : 178 | |||
Hashmueli, Sharon | Ramot-Naftali, IL | 13 | 141 |
# of filed Patents : 13 Total Citations : 141 | |||
Lewkowicz, Ayala | Kfar-Vradim, IL | 14 | 125 |
# of filed Patents : 14 Total Citations : 125 | |||
Shaaltiel, Yoseph | Kibbutz HaSolelim-Doar-Na HaMovil, IL | 43 | 445 |
# of filed Patents : 43 Total Citations : 445 |
Cited Art Landscape
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Patent Citation Ranking
- 2 Citation Count
- A61K Class
- 11.97 % this patent is cited more than
- 15 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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