INDICATOR CELL LINES AND METHODS FOR MAKING SAME

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20100190160A1
SERIAL NO

12524264

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Methods of making an indicator cell are described. The methods include, e.g., contacting a vertebrate cell comprising a functional endogenous target gene under control of an endogenous inducible promoter with a parvoviral vector comprising a construct comprising a targeting DNA sequence linked to a DNA encoding a reporter gene, wherein the construct enters the cell and undergoes homologous recombination with the target gene, thereby operably linking the reporter gene and the target gene; inducing expression of the target gene thereby causing expression of the reporter gene; and selecting the cell based on expression of the reporter gene.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
SHRINERS HOSPITALS FOR CHILDREN2900 ROCKY POINT DRIVE TAMPA FL 33607

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fernandez, Sandra Portland, US 1 0
Hurlin, Peter J Portland, US 1 0
Russell, David Seattle, US 78 1702

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation