Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer
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United States of America Patent
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Issued Date -
Jul 29, 2010
app pub date -
May 21, 2008
filing date -
Jun 1, 2007
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Abstract
The present invention therefore provides novel approaches and strategies for efficient regulation of γδ T cells in vivo, in a subject, particularly a human subject or a non-human primate. The present invention now discloses particular compositions and methods that can be used to induce the proliferation of γδ T cells in vivo, in a subject. These compositions and methods employ the conjoint treatment of an individual with a γδ T cell activating compound and IL-2 and are particularly suited for immunotherapy in a subject, particularly in a subject having a cancer or an infectious disease.
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