De Novo Synthesis of Conjugates
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United States of America Patent
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Issued Date -
Jul 22, 2010
app pub date -
Mar 12, 2008
filing date -
Mar 12, 2007
priority date (Note) -
Abandoned
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Abstract
The invention provides methods for the preparation of small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a water-soluble oligomer composition. Such drugs are produced through modification of a synthetic pathway to attach the oligomer to an intermediate compound followed by completion of the synthetic path.
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