DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20100184134A1
SERIAL NO

12685544

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

This invention provides for a novel means of incorporating non-native amino acids into preselected positions of a protein using a cell-free synthesis system. The methods involve the use of non-orthogonal, native isoaccepting sense tRNAs that are encoded by the genetic code. Such methods allow for numerous non-native amino acids to be incorporated through the use of sense codons without having to rely upon orthogonal tRNA-synthetase pairs.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
SUTRO BIOPHARMA INC111 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gold, Daniel South San Francisco, US 8 39
Murray, Christopher James Soquel, US 4 39
Rozzelle, James Edward San Francisco, US 2 11
Uter, Nathan South San Francisco, US 2 11
Voloshin, Alexei M South San Francisco, US 15 63
Yin, Gang South San Francisco, US 47 239
Zawada, James F South San Francisco, US 3 11

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation