Mannose immunogens for HIV-1
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United States of America Patent
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app pub date -
Feb 3, 2010
filing date -
Mar 16, 2005
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Abandoned
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Abstract
Methods of producing a carbohydrate HIV vaccine or immunogenic composition are provided. One method comprises expressing a glycoprotein with a modified glycosylation, which facilitates binding of the glycoprotein to the 2G12 antibody. Another method comprises iteratively selecting cells with a high affinity for the 2G12 antibody.
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