METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES
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United States of America Patent
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Issued Date -
Jul 15, 2010
app pub date -
Feb 13, 2008
filing date -
Feb 13, 2007
priority date (Note) -
Abandoned
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Abstract
gas), an adenosine pathway antagonist and/or an HIF-1α antagonist, and/or inhibitors of enzymes that produce or generate adenosine with the administration of the vaccine to the patient.The present invention also relates to methods of inducing or enhancing immune responses, methods of treating subjects having a tumor, methods of ablating or killing tumor cells and methods of disrupting the blood supply to a tumor, comprising administering oxygen alone or in combination with therapeutic agents that prevent inhibition of anti-tumor T cells. Tumor defense-resistant immune cells, anti-viral immune cells, and methods of their production are also disclosed.
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