Certain Chemical Entities, Compositions and Methods
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United States of America Patent
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Issued Date -
Jul 8, 2010
app pub date -
Jul 31, 2007
filing date -
Aug 1, 2006
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Abandoned
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Abstract
Provided are certain chemical entities, and methods of use to modulate diskeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, muscle spasm, neuromuscular disease, and other indications.
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