NOVEL CHEMOTHERAPEUTIC AGENTS AGAINST INFLAMMATION AND CANCER
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United States of America Patent
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Issued Date -
Jul 1, 2010
app pub date -
Oct 12, 2007
filing date -
Oct 13, 2006
priority date (Note) -
Abandoned
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Abstract
Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4-hydroxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent antimitotic agent and inducer of apoptosis are provided. Formulations and methods for treatment of diseases mediated by NF-kappaB are also provided.
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