OLIGONUCLEOTIDES FOR DISCRIMINATING RELATED NUCLEIC ACID SEQUENCES

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United States of America Patent

APP PUB NO 20100167280A1
SERIAL NO

12377044

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Abstract

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An in vitro selection method is described which identifies oligonucleotide probes that discriminate amongst closely related nucleic acid sequences and which involves iterative hybridizations, including subtractive hybridization. Using the method, oligonucleotides are identified which can discriminate among human papilloma virus (HPV) subtypes. Corresponding methods and kits for the detection of nucleic acids are described, which methods and kits may be used in analytical, diagnostic, research and related applications.

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Patent Owner(s)

Patent OwnerAddress
CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE3175 CHEMIN DE LA CÔTE-SAINTE-CATHERINE SUITE 1 17 003 QUÉBEC H3T 1C5

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brukner, Ivan Montreal, CA 2 2
Krajinovic, Maja Montreal, CA 2 2
Labuda, Damian Montreal, CA 4 34

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