POLYMETHYLMETHACRYLATE BONE CEMENT COMPOSITION FOR CONTROLLED HYPERTHERMIA TREATMENT
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United States of America Patent
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Issued Date -
Jun 24, 2010
app pub date -
Dec 18, 2009
filing date -
Dec 22, 2008
priority date (Note) -
Abandoned
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Abstract
The invention relates to a polymethylmethacrylate bone cement composition that contains polymethylmethacrylate, radio-opaquer, methylmethacrylate and/or alkylmethacrylates, and an initiator system and comprises, in addition, ferromagnetic and/or superparamagnetic particles of a particle size of up to maximally 500 μm—which allows it to be heated by alternating magnetic fields—and further contains at least one biodegradable or biocompatible crystalline substance having a melting point in the range of 43-46° C. The cured cement can be used for local over-heating (hyperthermia) therapy in the absence of undesired temperature peaks.
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