NATURAL SKIN WHITENER: 4-HYDROXY-OXINDOLE-3-ACETIC ACID
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United States of America Patent
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Issued Date -
Jun 24, 2010
app pub date -
Oct 9, 2009
filing date -
Oct 9, 2008
priority date (Note) -
Abandoned
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Abstract
A cosmetic and dermatological composition comprises 2, 3-dihydro-4-hydroxy-2-oxo-1-H-indole-3-acetic acid (4-hydroxy-1-oxindole-3-acetic acid) as an active ingredient for use as a melanin inhibitor and as an anti-tyrosinase enzyme inhibitor. This composition is excellent as a skin whitening agent. Since it also has potent antioxidant and anti-irritant activities it is useful in a cosmetic composition for improving hyperpigmentation disorders of the skin.
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