Method for evaluation of compound using RSK1
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United States of America Patent
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Issued Date -
Jun 17, 2010
app pub date -
Jun 6, 2006
filing date -
Jun 7, 2005
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Abandoned
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Abstract
A method for evaluation of a compound comprising the steps of introducing an RSK1 gene into a cell to prepare a cell capable of expressing RSK1, contacting a compound to be evaluated with the cell, and detecting the specific binding of the compound to RSK1; and a compound given by the method. The compound can be used as a potentiator of cisplatin. The method enables to find a gene which acts specifically on a cell of cancer induced by the abnormality in p53 or enhanced MAPK pathway and to evaluate a compound by using the gene.
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