SUBSTITUTED AZETIDINONES

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United States of America Patent

SERIAL NO

12703610

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Abstract

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Compounds are provided which have the structureWherein A, B, C, D, m, Y, Ra, Rc, Rd, and Rd′ are as described herein, and which are useful as inhibitors of tryptase, thrombin, trypsin, Factor Xa, Factor VIIa, Factor XIa, and urokinase-type plasminogen activator and may be employed in preventing and/or treating asthma, chronic asthma, allergic rhinitis, and thrombotic disorders.

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Patent Owner(s)

Patent OwnerAddress
DAIAMEDCAMBRIDGE MA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bannister, Thomas Palm Beach Gardens, US 8 52
Celatka, Cassandra Hull, US 25 135
Chandrakumar, Nizal S North Grafton, US 28 235
Deng, Hongfeng Acton, US 22 305
Guo, Zihong Southbury, US 45 3446
Jin, Lei Wellesley, US 207 2561
Lazarova, Tsveltelina Brookline, US 1 3
Lin, Jian Walpole, US 246 3476
Moe, Scott T Marlborough, US 37 816
Nagafuji, Pamela Cambridge, US 3 25
Navia, Manuel Lexington, US 6 27
Ripka, Amy Winthrop, US 50 606
Rynkiewicz, Michael J Boston, US 4 201
Spear, Kerry L Concord, US 51 500
Stickler, James E Milton, US 3 25
Xie, Roger Southborough, US 15 518

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