Methods of Reducing Repeat-Induced Silencing of Transgene Expression and Improved Fluorescent Biosensors
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United States of America Patent
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Issued Date -
Jun 3, 2010
app pub date -
Oct 14, 2005
filing date -
Oct 14, 2005
priority date (Note) -
Abandoned
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Abstract
Methods of avoiding repeat- and homology-induced silencing of transgenes are disclosed, in which transgene sequences are genetically altered to reduce the affects of gene silencing. FRET biosensors containing such genetic alterations for improved expression in cell lines and in vivo are disclosed.
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International Classification(s)
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A01K:ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; ....
- A01H:NEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT ....
- C07K:PEPTIDES
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