PROCESS FOR PREPARING THERAPEUTIC PEPTIDE
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United States of America Patent
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Issued Date -
Jun 3, 2010
app pub date -
Dec 3, 2009
filing date -
Dec 3, 2008
priority date (Note) -
Abandoned
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Abstract
This application discloses processes for synthesizing human relaxin Chain B for treatment of diseases mediated by relaxin. This application in particular discloses processes of synthesizing the Chain B of human relaxin using a solid and solution phase (“hybrid”) approach. Generally, the approach includes synthesizing three different peptide intermediate fragments using solid phase chemistry. Solution phase chemistry is then used to couple the fragments.
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