DOUBLE-STRANDED OLIGONUCLEOTIDES
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United States of America Patent
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app pub date -
Apr 3, 2008
filing date -
Feb 1, 2002
priority date (Note) -
Abandoned
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Abstract
Antisense sequences, including duplex RNAi compositions, which possess improved properties over those taught in the prior art are disclosed. The invention provides optimized antisense oligomer compositions and method for making and using the both in in vitro systems and therapeutically. The invention also provides methods of making and using the improved antisense oligomer compositions.
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