METHOD FOR DETECTING THE BINDING BETWEEN MDM2 AND THE PROTEASOME
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United States of America Patent
Stats
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N/A
Issued Date -
May 27, 2010
app pub date -
Apr 26, 2007
filing date -
Apr 26, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This invention provides both nucleic acid and amino acid sequences encoding for isolated protein-HDM2 binding sites as well as for isolated protein-proteasome binding sites (the ED(X)Y sequences). In a further aspect this invention also provides related nucleic acids, amino acids, vectors, host cells, pharmaceutical compositions and articles of manufacture. This invention further provides methods for determining whether a test compound interacts with the binding between HDM2 and the proteasome, as well as pharmaceutical compositions comprising said test compound, in particular as anti-cancer agent, even more particular for treating cell proliferative disorders in a subject.
First Claim
Other Claims data not available
Family
| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| PA | A1 | PA8778601 | Apr 24, 2008 |
| WO | A2 | WO2008132155 | Apr 25, 2008 |
| TW | A | TW200912000 | Apr 25, 2008 |
| CN | A | CN101790583 | Apr 25, 2008 |
| AR | A1 | AR066149 | Apr 25, 2008 |
| JP | A | JP2010529418 | Apr 25, 2008 |
| CA | A1 | CA2683071 | Apr 25, 2008 |
| CL | A1 | CL2008001213 | Apr 25, 2008 |
| EP | A1 | EP2140019 | Apr 25, 2008 |
| WO | A1 | WO2008132175 | Apr 25, 2008 |
International Classification(s)
- 2007 Application Filing Year
- C12N Class
- 4103 Applications Filed
- 1800 Patents Issued To-Date
- 43.88 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- C12N Class
- 12.47 % this patent is cited more than
- 15 Age