METHODS AND MATERIALS FOR THE GENERATION OF REGULATORY T CELLS

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United States of America Patent

SERIAL NO

12604263

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are disclosed for the generation of immunosuppressive regulatory T cells. The methods can include contacting a population of CD4+CD25− T cells with a T cell receptor (TCR)/CD3 activator, a TCR co-stimulator activator, and rapamycin. Kits for the generation of immunosuppressive regulatory T cells, methods of use, and cell populations are also disclosed.

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Patent Owner(s)

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INVITROGEN DYNAL ASOSLO

International Classification(s)

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  • 2009 Application Filing Year
  • A61K Class
  • 10313 Applications Filed
  • 6747 Patents Issued To-Date
  • 65.43 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200920102011201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arvak, Tanja Oslo, NO 1 4
Brunsvig, Anne Stabekk, NO 6 42
Kvalheim, Gunnar Oslo, NO 19 271
Piedras, Walter Gabriell Borelli Montevideo, UY 5 22
RASMUSSEN, Anne-Marie Oslo, NO 11 85

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  • 4 Citation Count
  • A61K Class
  • 11.97 % this patent is cited more than
  • 15 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7303334104243222310478582826113401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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