MULTI PORTION INTRA-ORAL DOSAGE FORM AND USE THEREOF
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United States of America Patent
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Issued Date -
May 20, 2010
app pub date -
Nov 14, 2008
filing date -
Nov 14, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a multi portion intra-oral dosage form where at least one portion is rapidly disintegrating and at least one portion is slowly disintegrating, whereby the disintegration time for the slowest disintegrating portion is at least two times longer than for the most rapidly disintegrating portion. Of certain interest is use of sensory markers/signals as conceptual aids for the subject.Also contemplated are a method and a system for delivering active agents, such as nicotine and/or metabolites thereof, such as cotinine, nicotine N′-oxide, nornicotine, (S)-nicotine-N-β-glucuronide and mixtures, isomers, salts and complexes thereof as well as use and production of said formulations.
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