SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY

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United States of America Patent

APP PUB NO 20100120798A1
SERIAL NO

12519993

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides compounds of the formula (I) having PKA and PKB kinase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP1: HET 2a a Q G (HNCO)f 7 (R)x N * (GP1) (2) GP is a group GP2: 10 (R)r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heterocyclic group containing up to 4 heteroatom ring members; the ring V is a monocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA ABSE-151 85 SODERTALJE
CANCER RESEARCH TECHNOLOGY LIMITEDANGEL BUILDING 407 ST JOHN STREET LONDON EC1V 4AD
ASTEX THERAPEUTICS LIMITED436 CAMBRIDGE SCIENCE PARK MILTON ROAD CAMBRIDGE CB4 0QA
THE INSTITUTE OF CANCER RESEARCH ROYAL CANCER HOSPITALLONDON SW7 3RP

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Caldwell, John Sutton, GB 76 1581
Carr, Gregory Richard Cheshire, GB 3 15
Cheung, Kwai Ming Staines, GB 12 108
Collins, Ian Redhill, GB 93 1712
Da, Fonseca McHardy Tatiana Faria Sunbury-on-Thames, GB 4 9
Hamlett, Christopher Cambridge, GB 4 3
Luke, Richard William Arthur Cheshire, GB 25 170
Matusiak, Zbigniew Stanley Cheshire, GB 17 50
Morris, Jeffrey James Cheshire, GB 14 237
Sore, Hannah Fiona Cambridge, GB 11 102
Verdonk, Marinus Leendert Burwell, GB 13 119
Walker, David Winter Cambridge, GB 25 158
Woodhead, Steven John Cambridge, GB 32 655

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